S-denosyl methionine(SAME), a biological compound participating in methyl group transfer, is present in all living cells. It is synthesized endogenously from adenosine triphosphate(ATP) and methionine adenosyl transferase.
Transmethylation, transsulfuration and aminopropylation are the metabolic pathways that use SAMe. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.
The activated methyl group(CH3)in SAMe allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group of SAM to various substrates such as nucleic acids, proteins and lipids.
SAMe is a good nutrition for the liver
SAMe has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heartdisease, cancer.
SAMe has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.
ASSAY: 95%~ 103%
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